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KMID : 0613820130230030443
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Journal of Life Science
2013 Volume.23 No. 3 p.443 ~ p.447
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Antimicrobial and Anti-oral Malodor Efficacy of Schizandra chinensis Extracts against Oral Pathogens
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Heo Nam-Suk
Choi Hye-Jung
Hwang Su-Mi
Choi Young-Whan
Lee Young-Geun
Joo Woo-Hong
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Abstract
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This study was conducted to investigate the antimicrobial and anti-oral malodor effect of Schizandra chinensis extracts against oral pathogens. S. chinensis methanol (MeOH) extract showed better antimicrobial activities against oral pathogens than the S. chinensis hot water extract did. In particular, ethylacetate (EA) fraction of S. chinensis MeOH extract had the greatest effects against Streptococcus mutans, S. sanguinis, S. salivaris subsp. thermophols and Porphyromons gingivalis. The anti-malodor effect of S. chinensis against the generation of volatile sulfur compounds (VSC), such as hydrogen sulfide, methyl mercaptan, and dimethyl sulfide, was estimated using oral chroma in a practical study. The results showed that 2% MeOH extract of S. chinensis against the production of hydrogen sulfide, methyl mercaptan, and dimethyl sulfide had inhibitions of 91.15, 78.72 and 71.58%, respectively. These results showed that Schizandra chinensis extract had antimicrobial activity against several oral pathogens and exhibited significant effects on the inhibition of VSCs. Thus, Schizandra chinensis extract could be an alternative to available synthetic chemicals and oral hygiene products.
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KEYWORD
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Antimicrobial activity, anti-oral malodor effect, Schizandra chinensis, oral pathogens
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